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As an alternative, the SDS should include a referral mechanism through which advice on treatment is available from a physician board-certified in medical toxicology.If one is not available, advice can be obtained from a poison control center.We recommend identification of drugs or toxins by careful history and targeted testing.An observation period of longer than five half-lives is appropriate when there is a possibility of an extremely large drug overdose, delayed drug absorption, delayed elimination, or interaction with another agent.In economics, physical capital or just capital is a factor of production (or input into the process of production), consisting of machinery, buildings, computers, and the like.

Drug screening in the clinical setting is not comprehensive, so a negative drug screen does not exclude intoxication.

Disclaimer While individual practitioners may differ, this is the position of the College at the time written, after a review of the issue and pertinent literature.

References The position of the American College of Medical Toxicology, endorsed by the American Academy of Clinical Toxicology and the Society of Critical Care Medicine, is as follows: We agree with the American Academy of Neurology (AAN) recommendation that the clinical determination of brain death should only be made in the absence of drug intoxication or poisoning.

Routine urine toxicologic immunoassays have limited sensitivity, even for common drugs, and a "negative" urine drug screen should not be used to exclude drug intoxication, and a "positive" urine drug screen cannot be used to assess the extent or degree of intoxication.

For example, a typical opiate screen does not reliably identify oxycodone and hydrocodone and does not identify synthetic opioids such as fentanyl or buprenorphine, and a typical benzodiazepine screen does not reliably identify clonazepam.

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